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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RECQL4
All Species:
6.97
Human Site:
T425
Identified Species:
19.17
UniProt:
O94761
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94761
NP_004251.2
1208
133077
T425
R
P
A
S
E
E
D
T
D
A
V
G
P
E
P
Chimpanzee
Pan troglodytes
XP_520023
1208
133141
T425
L
P
A
S
E
K
D
T
D
P
V
G
P
E
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_539222
1209
131690
T423
L
P
V
S
E
E
D
T
E
P
A
G
P
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q75NR7
1216
135105
A442
V
A
Q
R
T
G
T
A
S
C
H
H
S
G
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I920
1142
126164
I406
R
T
N
Q
L
E
A
I
N
A
A
L
L
G
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920631
1380
154059
K606
A
D
G
D
S
S
E
K
E
E
Q
G
A
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393782
1284
145763
D535
D
L
W
E
P
I
E
D
E
E
I
L
C
G
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001187631
1990
223246
E930
Q
P
G
N
L
A
D
E
G
R
G
D
K
F
E
Poplar Tree
Populus trichocarpa
XP_002315627
901
101082
K262
E
G
Q
L
E
A
I
K
M
V
L
D
G
K
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
N.A.
57.8
N.A.
65.9
N.A.
N.A.
N.A.
21.1
N.A.
41.2
N.A.
N.A.
33.2
N.A.
27
Protein Similarity:
100
99.2
N.A.
66.7
N.A.
75
N.A.
N.A.
N.A.
35.4
N.A.
56.5
N.A.
N.A.
51.3
N.A.
39.3
P-Site Identity:
100
80
N.A.
60
N.A.
0
N.A.
N.A.
N.A.
20
N.A.
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
86.6
N.A.
66.6
N.A.
0
N.A.
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
20
N.A.
26.6
Percent
Protein Identity:
25
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
42
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
23
0
0
23
12
12
0
23
23
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% C
% Asp:
12
12
0
12
0
0
45
12
23
0
0
23
0
0
0
% D
% Glu:
12
0
0
12
45
34
23
12
34
23
0
0
0
45
34
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
12
23
0
0
12
0
0
12
0
12
45
12
34
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% H
% Ile:
0
0
0
0
0
12
12
12
0
0
12
0
0
0
12
% I
% Lys:
0
0
0
0
0
12
0
23
0
0
0
0
12
12
0
% K
% Leu:
23
12
0
12
23
0
0
0
0
0
12
23
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
0
12
12
0
0
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
45
0
0
12
0
0
0
0
23
0
0
34
0
23
% P
% Gln:
12
0
23
12
0
0
0
0
0
0
12
0
0
0
0
% Q
% Arg:
23
0
0
12
0
0
0
0
0
12
0
0
0
0
12
% R
% Ser:
0
0
0
34
12
12
0
0
12
0
0
0
12
0
12
% S
% Thr:
0
12
0
0
12
0
12
34
0
0
0
0
0
0
0
% T
% Val:
12
0
12
0
0
0
0
0
0
12
23
0
0
0
0
% V
% Trp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _